What is the evidence of uncertainty?Interstitial cystitis

Two distinct types of disease classic and non ulcer interstitial cystitis have been described on the basis Buy of pathological findings, and some treatments might work better for one type than for the other.1 Currently no treatment ladder exists. Oral treatments should be first line and intravesical therapies second line. Interstitial cystitis is used alone when describing cases that meet criteria of the US National Institute of Diabetes and Digestive and Kidney Diseases.Patients with interstitial cystitis vary greatly in type and severity of symptoms, and the symptoms overlap with those of painful bladder syndrome and many other clinical entities.What is the evidence of uncertainty?Interstitial cystitis currently has no standard treatment.Results for oral L arginine, a substrate for nitric oxide synthesase, are also conflicting.

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